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PQQ Caps with BioPQQ 20mg (30)

PQQ Caps with BioPQQ®
20 mg 30 vegetarian capsules

Item Catalog Number: 01647

Mitochondria are the cellular energy generators that supply virtually all the power your body requires for a healthy life span. An abundance of published studies underscores the critical importance of the mitochondria to overall health, especially as we age.1-7 Energy-intensive organs like the heart and brain are dense withmitochondria. Until recently, the only natural ways for aging individuals to increase the number of mitochondria in their bodies were long-term calorie restriction or exhaustive physical activity—which are difficult or impractical for most people to implement. PQQ offers a viable alternative.

The enormous amount of energy generated within the mitochondria exposes them to constant free radical activity. The resulting mitochondrial decay is a hallmark of aging. PQQ protects and augments delicate mitochondrial structures to promote youthful cellular function in three distinct ways:

  • Antioxidant power. Like CoQ10, PQQ is a highly potent antioxidant. Its extraordinary molecular stability enables it to facilitate thousands of biochemical reactions in the mitochondriawithout breaking down, for maximum antioxidant and bioenergetic support.8
  • Favorably modulates gene expression. PQQ activates genes that promote formation of new mitochondria9—and beneficially interacts with genes directly involved in mitochondrial health. These same genes also support healthy body weight, normal fat and sugar metabolism, and youthful cellular proliferation.10
  • Mitochondrial defense. Mitochondria possess their own DNA, distinct from the DNA contained in the nucleus. Unfortunately, compared to nuclear DNA, mitochondrial DNA are relatively unprotected. PQQ’s antioxidant potency and favorable gene expression profile act to support mitochondrial defense.

PQQ is an essential nutrient, meaning that your body cannot make it on its own. A growing body of research indicates that PQQ’s unique nutritional profile supports heart health and cognitive function—alone and in combination with CoQ10.11,12 This comes as no surprise, given how much energy these vital organs need.

Research shows that PQQ supports heart cell function in the presence of free radicals and promotes blood flow in the heart muscle.13 When taken in combination with CoQ10, just 20 mg per day of PQQ has been shown to promote memory, attention, and cognition in maturing individuals.14

Life Extension has identified a purified, highly potent form of PQQ from Japan that is produced through a unique fermentation process. The result is BioPQQ®, the highest quality PQQ available on the market today.

References 
1. Biochimie. 1999 Dec;81(12):1131-2. 
2. Lancet. 1989 Mar 25;1(8639):642-5. 
3. Curr Opin Clin Nutr Metab Care. 2010 Jul 7. 
4. Age (Dordr). 2010 Mar 20. 
5. Ageing Res Rev. 2010 Jun 25. 
6. Cell Mol Life Sci. 2010 Jun 25.
7. Zhonghua Yi Xue Za Zhi (Taipei). 2001 May;64(5):259-70.
8. Alt Med Rev. 2009; 14(3):268-77. 
9. J Biol Chem. 2010. Jan 1;285:142-152
10. Entrez Gene: PARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha [ Homo sapiens ] GeneID: 10891.
11. Cardiovasc Drugs Ther. 2004 Nov;18(6):421-31. 
12. J Cardiovasc Pharmacol Ther. 2006 Jun;11(2):119-28.
13. Biochem Biophys Res Commun. 2007 Nov 16;363(2):257-62.
14. FOOD Style. 2009;21:13(7)50-3. [Tokyo].
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N-Acetyl-L-Cysteine 600mg (60)

N-Acetyl-L-Cysteine
600 mg, 60 vegetarian capsules Item Catalog Number: 01534

L-cysteine is a conditionally essential amino acid, one of only three sulfur-containing amino acids, the others being taurine (which can be produced from L-cysteine) and L-methionine (from which L-cysteine can be produced in the body by a multi-step process). Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine.136-138 Cysteine also helps synthesize glutathione, the body’s most important intracellular antioxidant and a vital detoxifier.139-142

N-acetyl-L-cysteine (NAC) is the acetylated form of L-cysteine that has been used to break up pulmonary and bronchial mucous.143-146 It is very efficiently absorbed and has been shown to protect cells directly and support the immune system.146-155 NAC is an antioxidant and a free radical-scavenging agent that increases intracellular glutathione at the cellular level. NAC can act as a precursor for glutathione synthesis as well as a stimulator of the cytosolic enzymes involved in glutathione regeneration.146 NAC has been shown to protect against oxidative stress-induced neuronal death in cultured granule neurons.156

References
SUPPLEMENT FACTS
Supplement Facts
Serving Size 1 vegetarian capsule
Amount Per Serving
N-acetyl-L-cysteine
600 mg
Other ingredients: vegetable cellulose (capsule), vegetable stearate, silica.
Non-GMO
Dosage and Use
Take one (1) capsule one to three times daily with or without food, or as recommended by a healthcare practitioner.
Caution
Those who supplement with NAC should drink 6 to 8 glasses of water daily in order to prevent cysteine renal stones. Cysteine renal stones are rare but do occur.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.

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Life Extension Buffered vitamin C (454g)

Buffered Vitamin C Powder 454 gram

Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress.1-8 Vitamin C also promotes the absorption of iron, while preventing its oxidation.9,10 Vitamin C is a vital cofactor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth.4-6 A major immune-supporting activity of vitamin C is boosting glutathione levels in human lymphocytes,38 cells that make up about 25% of all white cells in the blood.

More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress.11-14 Physical stresses on the body such as ingestion of heavy metals,15-20 cigarette smoking,21-24 immune impairment,25-31 extreme temperatures,31-36 and chronic use of certain medications such as aspirin also signal the need for increased intake of vitamin C.37

Vitamin C Powder contains four buffering minerals, in addition to ascorbic acid. When mixed with water, this product produces a reduced-acid solution that is non-irritating to the stomach and intestinal lining. The minerals also make it a more pleasant-tasting and healthful drink. The substances used in this product make it effervesce for a short while when it is mixed with water.

Food Supplement 454 g
Serving Size: 1 rounded teaspoon (approximately 5 g)
Amount per Serving
Vitamin C (as ascorbic acid) 4000 mg
Calcium (as calcium carbonate) 145 mg
Magnesium (as magnesium carbonate) 55 mg
Zinc (as zinc gluconate) 2 mg
Potassium (as potassium carbonate) 365 mg

RI = EU Reference Intake, * no RI available.

Ingredients: Ascorbic acid, calcium carbonate, magnesium carbonate, zinc gluconate, potassium carbonate.

Dosage and use
Mix one (1) teaspoon of Buffered Vitamin C Powder into a glass of water. Wait for the fizz to stop before consuming. The minerals buffer out normally acidic vitamin C to make a pleasant tasting drink. To ensure product consistency store tightly closed in a cool, dry place.

Caution
This product may cause diarrhoea, if taken in high doses, especially on an empty stomach. For optimal benefits, begin with low doses during meals and gradually increase it.

References
1. Biochim Biophys Acta. 2012 Dec;1826(2):443-57.
2. Redox Rep. 2010;15(1):11-9.
3. Adv Nutr. 2011 Mar;2(2):78-88.
4. Altern Med Rev. 2003 Nov;8(4):359-77.
5. J Invest Dermatol. 2002 Apr;118(4):565-72.
6. Radiat Environ Biophys. 2007 Mar;46(1):61-8.
7. Free Radic Biol Med. 2007 Sep 1;43(5):853-9.
8. PLoS Negl Trop Dis. 2012;6(7):e1729.
9. Br J Nutr. 2003 Dec;90(6):1081-5.
10. Am J Clin Nutr. 2006 Oct;84(4):830-4.
11. In Vivo. 1994 Nov-Dec;8(6):1079-85.
12. Ann Nutr Metab. 1990;34(2):85-92.
13. Psychopharmacology (Berl). 2002 Jan;159(3):319-24
14. Am J Clin Nutr. 2007 Jul;86(1):145-9.
15. Genet Test Mol Biomarkers. 2012 Sep;16(9):1001-6.
16. Environ Toxicol Pharmacol. 2011 Jan;31(1):137-42.
17. Acta Biochim Biophys Sin (Shanghai). 2012 Apr;44(4):330-8.
18.Nig Q J Hosp Med. 2012 Apr-Jun;22(2):85-90.
19. Toxicology. 2005 Jul 1;211(1-2):26-35.
20. Chem Biol Interact. 2001 Jul 31;137(1):75-88.
21. Environ Health Perspect. 2000 Feb;108(2):105-8.
22. Am J Ther. 2007 Mar-Apr;14(2):189-93.
23. Am J Clin Nutr. 2000 Feb;71(2):530-6.
24. Toxicology. 2002 Nov 15;180(2):121-37.
25. J Am Coll Cardiol. 2003 Nov 5;42(9):1656-62.
26. J Pediatr Gastroenterol Nutr. 2003 Jul;37(1):53-62.
27. Cancer Sci. 2003 Apr;94(4):378-82.
28. Adv Ther. 2002 May-Jun;19(3):151-9.
29. Br J Dermatol. 1980 Jan;102(1):49-56.
30. Respir Med. 2007 Aug;101(8):1770-8.
31. Acta Obstet Gynecol Scand. 2007;86(7):783-7.
32. J Int Med Res. 2012;40(1):28-42.
33. Vopr Pitan. 1978 Jan-Feb;(1):44-8.
34. J Am Coll Nutr. 1990 Apr;9(2):150-4.
35. Jpn J Physiol. 1999 Apr;49(2):159-67.
36. Indian J Med Res. 2002 Jul;116:29-34.
37. Med Sci Monit. 2001 Jul-Aug;7(4):592-9
.

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Cran-Max Cranberry whole fruit consentrate 500mg (60) veg caps

Cran-Max® Cranberry Whole Fruit Concentrate

Cran - Max contains concentrated cranberry made from the complete cranberry using a unique process, with no added sugar. Each capsule of this product contains powerful polyphenols, organic acids and antioxidants that provide the same benefits as drinking cranberry juice cocktail minus calories. An advantage of Life Extension’s Cran-Max® is that it only requires once a day dosing.

The anatomy of the female urinary tract differs greatly from men, resulting in the need for additional nutritional support for women. A wealth of published studies indicates that cranberry polyphenols may help to support a healthy urinary tract.63-67

Cranberries have been known for decades to promote a healthy urinary tract. Clinical research demonstrates that cranberries’ proanthocyanidins are powerful antioxidants that can reduce oxidative stress.72 A double-blind comparison study confirms that Cran-Max® helps support a healthy urinary tract.73 Each Life Extension Cran-Max® capsule contains 500 mg of cranberry concentrate to promote urinary tract health.66,74-84 Each Cran-Max® capsule also contains:

The synergistic, complete spectrum activity of the entire cranberry whole fruit
A unique delivery system that protects its cranberry constituents from degradation

Antioxidants
Cran-Max® contains concentrated cranberry made from the complete cranberry using a unique, patent-pending process. No sugar is added. Each capsule of Cran-Max® contains powerful polyphenols, organic acids, and antioxidants, providing the same benefits as drinking cranberry juice cocktail, but without the calories. An advantage of Life Extension’s Cran-Max® is that it only requires once a day dosing!

References (referanser) here!

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Beta-Carotene 25000IU (100)

Beta-Carotene
25,000 IU 100 softgels Item Catalog Number: 00664
Vitamin A (retinol) is a yellow, fat-soluble, generic term for a large number of related compounds obtained from some carotenoids by conversion in the liver, its storage organ. Retinol (an alcohol) and retinal (an aldehyde) are often referred to as preformed vitamin A. While carotenoids are widely distributed in such foods as green and yellow vegetables, retinol is not found in any vegetable sources, but is concentrated in egg yolks and the livers of many animals. Vitamin A, either from animal sources or synthesized in our own liver, is essential for growth and reproduction, maintaining healthy vision, and supporting protein synthesis and cell differentiation.

Vitamin A and its analogs have shown the ability to help maintain proper DNA function.1-3 One study, however, has shown that for certain lifestyles (e.g., smokers) supplemental intake of too much beta-carotene in the absence of other carotenoids and antioxidants (such as at least 400 IU/day of vitamin E) may be harmful.4

Beta-carotene is the most potent precursor to vitamin A, but its conversion to vitamin A in the body is limited by a feedback system. It is an important antioxidant in its own right and one that can only build up to toxic levels in rare circumstances. Beta-carotene helps support immune health by enhancing the function of the thymus gland.5,6

References
1. Cell Mol Life Sci. 2004 Jun;61(12):1475-84.
2. Curr Cancer Drug Targets. 2004 May;4(3):285-98.
3. Nutr Cancer. 2002;42(1):117-24.
4. Biochim Biophys Acta. 2002 Feb 20;1574(1):85-92.1. JAMA. 2003 Jul 23;290(4):476-85.
5. Eksp Klin Farmakol. 1993 Jan-Feb;56(1):49-51.
6. Vopr Med Khim. 1992 Nov-Dec;38(6):31-3.

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Advanced Curcumin Elite (30)

  • Up to 7 times higher absorption rate
  • Inhibits inflammatory factors
  • Augmented with turmeric oil & ginger extracts

Our Super Bio-Curcumin formula delivers the patented turmeric extract, BCM-95, which is up to seven times more absorbable than conventional curcumin and lasts longer in your bloodstream.

 

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