PalmettoGuard® Saw Palmetto with Beta-Sitosterol

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Quick Overview

PalmettoGuard® Saw Palmetto with Beta-Sitosterol
Published studies suggest that a remarkably high percentage of men will endure some form of prostate-induced discomfort over the course of their lifetimes.Decades of research substantiate saw palmetto as the gold standard in natural prostate support. The saw palmetto berry (Serenoa repens) is rich in bioactive, high-molecular weight compounds including beta-sitosterol. It has been shown to interfere with DHT activity in the prostate, inhibit alpha-adrenergic receptor activity (to support normal urinary flow), and help regulate inflammatory actions in the prostate gland. This saw palmetto extract has been standardized to contain 85% free fatty acids and sterols. It also contains beta-sitosterol, boron, and rosemary leaf extract.

With age, many men experience urinary tract and prostate issues. Berry extracts from the Saw Palmetto plant found in PalmettoGuard® Saw Palmetto with Beta-Sitosterol can support prostate health and thereby normal urinary tract function.The saw palmetto berry (Serenoa repens) is rich in bioactive, high-molecular-weight compounds including beta-sitosterol. It is from the saw palmetto berry, that the extracts found in PalmettoGuard Saw Palmetto with Beta-Sitosterol have been pulled. These have been shown to interfere with DHT (dihydrotestosterone) activity in the prostate thereby supporting normal urinary flow, and help regulate inflammatory response in the prostate gland. The saw palmetto berry extract in PalmettoGuard® Saw Palmetto with Beta-Sitosterol has been standardized to contain 85% free fatty acids and sterols. It also contains beta-sitosterol, boron, and rosemary leaf extract for extra prostate support.

 

The Science Behind the Product:

 

Saw palmetto berry extract has been shown to interfere with dihydrotestosterone (DHT) activity in the prostate by helping to prevent the conversion of testosterone to its potent metabolite dihydrotestosterone . Furthermore, it was shown to suppress alpha-adrenergic receptor activity (to support normal urinary flow), and help regulate inflammatory actions in the prostate gland. Research reported that supplementation with saw palmetto supports prostate health and thereby normal urinary tract function. Furthermore, some evidence shows that supplementing with saw palmetto may also positively modulate the complex system of hormone metabolism in men.

 

 

Saw palmetto berry extract for healthy prostate function
PalmettoGuard Saw Palmetto with Beta-Sitosterol:

  • Helps regulate a normal inflammatory response in the prostate gland
  • Plays a role in countering age-related prostate issues
  • Supports normal urinary function
  • Berry extracts from Saw Palmetto can support a healthy prostate function in the aging male body. see above

 

Supplement Facts
Serving Size 1 softgel 
Amount Per Serving
Calories 5
Calories from Fat 5
Total Fat 0.5 g
Saturated Fat 0 g 
Cholesterol 0 mg
Saw Palmetto CO2 extract (fruit) [providing 272 mg total fatty acids] 320 mg
Beta-sitosterol (from pine) 90 mg
Boron (as Albion® bororganic glycine) 3 mg
Rosemary extract (leaf) 400 mcg
Other ingredients: pumpkin seed oil, gelatin, glycerin, sunflower lecithin, purified water, caramel color.

Non-GMO. Albion® is a registered trademark of Albion Laboratories, Inc.

Dosage and Use
Take one (1) softgel daily with or without food, or as recommended by a healthcare practitioner.

Tillatt brukt for voksne over 18 år. All bruk av tilskudd foregår på eget ansvar og bør skje i samråd med lege. Anbefalt døgndose bør ikke overskrides. Kosttilskudd bør ikke erstatte et variert kosthold. Bør oppbevares utilgjengelig for barn

Forbehold. Uno Vita hevder ikke at produktene vi markedsfører kan kurere sykdom. 

 

 

Details

 

Prostate Supplements Review (Saw Palmetto and Beta-Sitosterol)

Summary
Two popular supplements for treating the symptoms of benign prostate hyperplasia (BPH) are saw palmetto and beta-sitosterol -- a compound derived from saw palmetto as well as other plants) (See What It Is). Beta-sitosterol has been found in most, but not all studies, to significantly improve perceived symptoms of BPH and urine rate flow (See Beta-Sitosterol — What It Does). Doses used in clinical studies range from 30 mg to 91 mg daily (See Beta-Sitosterol — What to Consider When Buying)
The evidence for saw palmetto is less impressive and recent studies have failed to show any benefit over placebo. It may help to shrink the inner lining of the prostate, but does not decrease its overall size. A typical dose is 320 mg per day of extract standardized to 85% to 95% fatty acids) (see Saw Palmetto -- What to Consider When Buying).
ConsumerLab.com's tests identified a number of saw palmetto and beta-sitosterol supplements which contained the generally recommended amounts of these ingredients. However, one saw palmetto product was found to contain fewer fatty acids than expected, and two saw palmetto/beta-sitosterol combination products were found to be improperly labeled. Beta-sitosterol and saw palmetto are generally well tolerated, although some individuals experience nausea or other gastrointestinal symptoms. 

Saw Palmetto
Saw palmetto (Serenoa repens) is a type of palm tree, also known as the dwarf palm, which mainly grows in the United States. Its primary medicinal value lies in the oily compounds found in its berries. Most dietary supplements are composed of an extract from the berries or a berry powder.

Beta-sitosterol
Beta-sitosterol is a type of phytosterol (plant-derived cholesterol-like compounds). Sources of beta-sitosterol include rice bran, wheat germ, corn oils, soybeans, avocados, pecans, and peanuts as well as saw palmetto, pumpkin seed, pygeum bark, and stinging nettle root. Extracts of African wild potato (also known as South African star grass) have been used to produce some clinically studied products consisting of a mixture of phytosterols in which beta-sitosterol is the main component.

What It Does:
Saw Palmetto:
Men with enlarged prostates (medically known as benign prostatic hyperplasia, or BPH) often experience difficulty with urinary flow, increased frequency and urgency of urination, and a fullness of the bladder after urination. Saw palmetto is believed to inhibit the actions of testosterone on the prostate that cause prostate enlargement and interference with urinary flow. It shrinks the inner epithelium of the prostate, but not the prostate's overall size. It has been believed that saw palmetto dietary supplements provide mild to moderate improvement in symptoms of prostate enlargement. However, the evidence of saw palmetto's benefit is conflicting and recent studies have failed to show any benefit over placebo.

A large and well designed study published in 2011 showed no greater improvement with saw palmetto extract than placebo (Barry, JAMA 2011). As an extra measure, that study used the standard dose of saw palmetto (320 mg per day of extract standardized to 85% to 95% fatty acids) as well as twice and three times the dose, each for 24 weeks. None showed a significant benefit. A large study published in 2006 also did not show a benefit with a different saw palmetto extract in men with moderate to severe symptoms. Only more limited studies have shown benefit in men with mild symptoms, or that saw palmetto may be as effective as the prescription drug finasteride (Proscar), but with fewer side effects. Alpha-blockers, meanwhile, may be more effective than saw palmetto.

Adding saw palmetto extract (320 mg daily of a liposterolic extract) to treatment with the alpha-blocker silodosin (Rapaflo) (8 mg daily), resulted in greater improvement in symptoms, with no increase in adverse effects, than with silodosin alone in a study in Italy lasting approximately 14 months. Young patients with severe symptoms appeared to benefit most (Boeri, Sci Reports 2018). In contrast, a study in Turkey using tamsulosin (Flomax) (0.4 mg daily) found no additional benefit from adding saw palmetto extract (320 mg daily) (Hizli, Int Urol Nephrol 2007).

A trial of saw palmetto (160 mg daily) for 5 weeks prior to transurethral prostatectomy (TURP) failed to decrease the density of prostatic tissue or lower the risk of bleeding during the procedure (Tuncel, Scan J Urol Nephrol 2009).

A preliminary study suggested that a saw palmetto extract with added beta-sitosterol (200 mg of saw palmetto standardized to 85% to 95% fatty acids and 50 mg of beta-sitosterol, given twice daily) may be effective against androgenic alopecia (male-pattern baldness). Over the course of the study, which averaged 4.6 months, improvement was seen in 6 of 10 men receiving the supplement, while only 1 of 9 men who received placebo experienced improvement (Prager, J Alt Comp Med 2002). However, the results were not considered to be statistically significant due to the small size of the study. The researchers noted that larger-scale studies would be designed, but none have been published to date. In a 2-year study of healthy men ages 20 to 40 with mild to moderate androgenic alopecia, 38% of those who took saw palmetto extract (320 mg daily -- percentage of fatty acids not provided) had an increase in hair growth, compared to 68% of those who took finasteride (1 mg daily) (Rossi, Int J Immunopathol Pharmacol 2012). However, the study did not compare these treatments to placebo. Interestingly, saw palmetto extract appeared to increase hair growth only on the balding area on the top of the head (vertex), while finasteride increased hair growth on the top of the head and the front hairline.

Although not supported by clinical evidence, saw palmetto has also been used to treat bladder inflammation (cystitis), chronic bronchitis, laryngitis, and asthma-associated nasal inflammation, among other conditions.

Among the main constituents of saw palmetto berry extract are fatty acids and sterols. The sterols (which include beta-sitosterol) are also present in other herbs (such as pygeum bark, stinging nettle root, and pumpkin seed extract) that are used in treating symptoms of prostate enlargement. Depending on the form of saw palmetto used, e.g., extract or whole dried berry, certain percentages of its weight should be expected (or "standardized") to specific fatty acids and specific sterols. These amounts are based on the composition of saw palmetto products that were shown to work in some clinical trials. (See How Products Were Evaluated for the expected amounts of fatty acids and sterols and see ConsumerTips™ for more information on dosing and usage).

Beta-sitosterol:
Most studies of beta-sitosterol, although not all, have found significant improvement in perceived symptoms of BPH and in urine flow rate. In addition, benefits seem to persist for months after treatment according to a follow up study that looked at men one year after treatment (Berges, Br J Urol 2000). Like the BPH drug finasteride (Proscar), beta-sitosterol may inhibit 5-alpha-reductase activity in the prostate. (See ConsumerTips™ for more information on dosing and usage of beta-sitosterol).

At a much higher dosage and in combination with other sterols, beta-sitosterol can also lower total cholesterol and LDL cholesterol levels when these supplements are consumed with meals (see ConsumerLab.com's Review of Cholesterol Lowering Supplements). In this case, beta-sitosterol works in the gut, where it reduces cholesterol absorption.

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manufacturerLife Extension
Tax ClassMomspliktige varer 15%

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