QHRV Pro + helsekontrollsystemet (EKG+)

€ 6,281

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Quick Overview



DanTest QHRV systems provide HRV testing which enable physicians to monitor the activity of both the sympathetic and parasympathetic branches of the autonomic nervous system (ANS) in order to accurately assess the state of a patient's autonomic function.

DanTest QHRV provides a two-pronged approach to patient evaluation. Firstly, DanTest QHRV is able to detect specific types of autonomic dysfunction which can consequently be linked to a multitude of clinical diagnoses. Secondly, DanTest QHRV can be utilized for thorough, comprehensive assessments and physiological monitoring which provide physicians with a detailed and thorough patient appraisal which can often be overlooked in standard evaluations.

The wide range of clinical applications for DanTest QHRV makes it principally different from all other classes of diagnostic devices. DanTest QHRV allows the physician to thoroughly investigate modalities:

* Assessment of resting autonomic balance
* Assessment of reaction of the ANS on orthostatic intervention
* Assessment of autonomic reaction during Valsalva maneuver and deep breathing
* Sympathetic and Parasympathetic autonomic balance correction

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Pulse Wave Velocity (PWV)
Pulse wave is a physiological phenomenon, observable and measurable in the arterial system during blood circulation. During one heart systole a certain blood volume is expelled. This propagates through the arteries due to the reciprocal transformation between kinetic energy of a segment of the expelled blood volume and the potential energy of a stretched segment of the resilient vascular wall. We can observe the changes in pressure, blood flow, velocity and profile throughout the whole pulse wave. It can be used for classification of the artery elasticity.

The condition of the small and large arteries is key to prevention and diagnosis of cardio-vascular related illness. In particular, the stiffness and augmentation of the major arteries is a strong indication of potential health problems including heart attacks, heart failure, sclerosis, and renal complications. PWV Analysis and arterial stiffness indexes (EEI, DDI and DEI) can suggest to healthcare professional to begin appropriate treatment long before the symptoms or clinical signs appear.

Age and systolic pressure strongly correlate with PWV. In fact, the most important factor contributing to increase in PWV is age because of increased arterial stiffness caused by medial calcification and loss of elasticity. The measurement of pulse wave velocity is useful in the study of the effects of aging, vascular diseases, vaso-dilating and vaso-constricting agents on arteries.

DanTest QHRV Pulse Wave Velocity measurement is a convenient method of quantifying arterial stiffness and augmentation. PWV provides invaluable insight into cardiovascular health, management of disease progression and monitoring the effects of medication, treatments, lifestyle and dietary habits.

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Segmental Vascular Assessment
Initial assessment is the most vital step in managing a patient’s health. As such, extracting as much information and achieving a broad road map of the arterial anatomy is crucial for proper arterial and vascular assessment. DanTest QHRV Arterial Vascular Assessment measures blood pressure uses the identical standard as conventional arm cuffs. While the traditional arm cuff method just measures blood pressure, the DanTest QHRV Arterial Vascular Assessment is a powerful measure which provides further insight into arterial stiffness.

The information collected during the DanTest QHRV Arterial Vascular Assessment using the upper arm cuff is disseminated into a wide range of measurements. This data is then extrapolated into a number of indexes and further classifications which include the following:

• Arterial Stiffness Index (ASI)
• Blood Pressure (Brachial, Ankle)
• Pulse Pressure
• Pulse Rate
• Classification of Cardiovascular Condition

The information deduced from the DanTest QHRV Arterial Vascular Assessment is invaluable for detecting risk factors and facilitating the identification of patients who may be at risk for cardiovascular events. Studies have shown that the Arterial Stiffness Index (ASI) illustrates a strong correlation between the functioning and integrity of coronary arteries and atherosclerotic lesions. This particular connection is significant in that atherosclerotic lesions are fatal yet may remain asymptomatic for decades. Over 60 million Americans carry these life-threatening issues so isolating high-risk individuals is most valuable.

The indexes generated by the DanTest QHRV Arterial Vascular Assessment are far-reaching and provide important patient insight into a number of existing and potential health risks. These cardiovascular issues include the following:

• Atherosclerosis
• Infectious vasculitis
• Congenital abnormalities
• Hypertension
• Hyperlipoproteinemia

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Peripheral Arterial Tone (PAT)
PAT (Peripheral Arterial Tone) technology measures arterial tone changes in peripheral arterial beds. This information collected gives specialists important insight into the autonomic nervous system as well as the cardiovascular system. PAT technology is a noninvasive measure that is currently used to detect heart disease, erectile dysfunction and obstructive sleep apnea, however, it has also proven highly effective in the detection and monitoring of other cardiovascular conditions.

As PAT data imparts early-stage information, PAT technology is highly valuable in disease detection and follow-up, thereby improving patient treatment and healthcare costs. In addition to detecting cardiovascular disease, the PAT system also presents potential for improving the diagnosis and management of other medical conditions including metabolic syndrome, diabetes, peripheral arterial disease and many others.

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Coronary Artery Respiratory Assessment (CRA)
Coronary artery disease (CAD) occurs when the blood vessels that transport blood to the heart are narrowed and hardened due to plaque buildup (atherosclerosis). This narrowing compromises the flow of nutrient-rich, oxygenated blood to vital organs which can lead to stroke, heart attack and death. In fact, coronary artery disease is the leading cause of death among American adults. As such, detection are treatment are at the forefront of relevance.

The photoplethysmograph (PPG) waveform has profound prognostic value for coronary artery disease. Studies show that fluctuations measured in photoplethysmograph (PPG) amplitude are directly related to coronary artery disease (CAD) and present powerful predictions of risk.

Photoplethysmograph (PPG) is measured using a non-invasive, radiation-free platform. This proprietary test system was developed by DanTest QHRV and utilizes a biosensor finger probe to collect data. The patient is then asked to perform a series of controlled breathing exercises. The coronary respiratory response (CRR) is derived from spectral analysis of the PPG signal during instructed breathing.

The PPG signal is automatically extracted and captured for processing. Using algorithms and analyzing software, a reading is produced which offers a timely and accurate diagnosis of Significant Coronary Artery Disease (S-CAD)

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Cumulative Stress Assessment
Stress means different things to different people. People recognize stress as a state of having too much expected of them, of being under pressure or strain, or of being barely able to cope with some external demand which is both excessive and prolonged. All of the symptoms carry the connotation of unreasonable demands being placed on the individual in an emotional, mental or psychological sense. A similar concept underlies the term stress in the medical sciences; a force exerted on a subject that, if not resisted, will damage or destroy it.

Stressors can be physical, mental or both. Physical stress is caused by long-term exposure to negative factors such as an irregular lifestyle, physical overload, environmental toxicity, cigarette/alcohol/drug use, improper diets, etc.

Mental stress can be caused by factors such as insecurity, negative emotions, mental overload, confusion, rejection on a social level, family problems, boredom, low self-esteem, etc.

Physical and mental stress each elicits physiological responses that are mediated through the autonomic nervous system. This autonomic nervous system (ANS) is both our major defense against stress and the system that demonstrates the principal symptomatic manifestation of stress in its early stages. The autonomic nervous system is conventionally divided into two parts in a yin/yang balance: the sympathetic, which activates organs, getting them ready to cope with exercise or other physical stress; and the parasympathetic, which controls background "housekeeping" functions in the body. The balance between these two systems is an indicator of the body's reaction to external and internal demands.

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Cardiovascular Fitness Test
Fitness Test It is widely recognized that Orthostatic testing is one of the most effective methods of measuring subtle changes in cardiovascular function, particularly the system's regulatory mechanisms. When performing the Orthostatic test, the patient sits down for several minutes resting peacefully and then stands up. When the body position shifts from supine or seated to standing, specific changes in heart rate and blood pressure occur as a compensatory reaction of the body. Testing helps to assess the ability of both sympathetic and parasympathetic nervous systems to adequately respond to regulatory challenge caused by gravitational shift in the body's blood mass. The test result (i.e. the orthostatic heart rate) is the difference between the heart rates at supine rest and at standing position.

For a healthy individual, standing up as well as maintaining the standing posture for several minutes causes no significant physical exertion. However, if there is subtle cardiovascular deficiency or the functional capacity of the body's regulatory mechanisms is inadequate then this maneuver becomes a significant stressor to the body.

DanTest QHRV Orthostatic testing is the quantitative and qualitative assessment of the fitness and health levels based on HRV analysis. The test is quick and effective and begins with the attachment of simple, noninvasive electrodes, attached as instructed. The candidate is instructed to stand for two minutes followed by sitting for 30 seconds followed by standing for 30 seconds. The full process is repeated alternately for three minutes. The data collected from mean cardio tachogram and spectrum is analyzed to produce eventual results in both quantitative and qualitative format.

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ECG Analysis
Electrocardiography (ECG) is an interpretation of the electrical activity of the heart over time as collected from a patient during the procedural test. Modern ECG devices use sophisticated techniques like amplification, filtering, and signal analysis to accurately and conveniently measure, display, and analyze ECG data. ECG is the most important test for interpretation of cardiac rhythm, conduction system abnormalities, and for the detection of myocardial ischemia.

Arrhythmic cardiac events, which may be extrasystoles (i.e. cardiac premature heart beats) are early warning signs for serious potential cardiac issues. The relation between supraventricular or ventricular extrasystoles and health risk is important because they can precede myocardial infarction. They are an early warning signal for possible cardiac problems as myocardial ischaemia ( a decreased oxygen supply to cardiac myofibers or different kinds of cardiomyopathy). Cardiomyopath is a disease or disorder of the heart muscle which can result from numerous conditions including congenital defects, acute or chronic infections, coronary artery disease, drugs and toxins, metabolic disorders, connective tissue disorders, or nutritional deficiencies.

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Exercise ECG Assessment
DanTest QHRV’s Exercise ECG is an all-inclusive, PC-based electrocardiogram testing system equipped with state-of-the-art technology for performing stress tests of the utmost accuracy. This low-cost, easy-to-use system enables users to simultaneously monitor 12 leads onscreen using programmable reports and protocols. Other highlights and benefits of DanTest QHRV’s Exercise ECG include the following:

• Utilizes wireless ECG sensors
• Automatically generates and prints reports
• Produces bit-to-bit blood pressure measurements
• Customizable stress protocols based on personal preference
• Produces all standard stress protocols
• Generates ST measurements for modification before, during or following completion of the test

A stress test, otherwise known as an exercise electrocardiogram, is a screening tool used to evaluate the effect of exercise on your heart and lungs. Because some heart issues only become apparent during exercise, the test utilizes a treadmill or stationary bicycle to produce results that can be tracked and measured. This noninvasive, diagnostic test measures your heart rate, blood pressure and electrocardiogram (or heart’s electrical activity) before, during and after exercise. The level of exertion is increased gradually during the test to ascertain whether or not the heart and lungs are receiving enough oxygen and performing properly.

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Overall Health Assessment
Establishing overall health level is key to disease prevention and optimized health. DanTest QHRV presents a systematic and convenient approach to calculating individual overall health. By combining the results of all DanTest QHRV procedural tests including the data collected from Pulse Wave Velocity assessment, ECG analysis, Autonomic Nervous System assessment, cumulative stress testing, fitness testing and correlation analysis a value for overall health is determined.

DanTest QHRV analyzes the potential for health problems by examining the body of data generated by thorough testing as compared to a database of over 50,000 test subjects. The resulting value is measured in a percentage of overall health risk with 50% relating to 'normal'. A value of over 50% is cause for concern and necessitates medical intervention. The value can be useful in understanding current physical state as well as recognizing resource depletion and reserves available for coping with future ailments.

Studies indicate that individuals with increased health risk are more prone to develop illness, including life-threatening disease, within the following few years of assessment. Determining overall health and risk of disease development is, therefore, vitally important to the prevention of serious illness and an important contribution to the wellbeing and longevity of individual life. Patients are able to address their current health issues and manage risks accordingly in order to improve overall health.

DanTest QHRV products provide the depth and breadth of information required to make informed decisions regarding therapy, treatment and important lifestyle changes. Products are professional medical solutions suitable for mass testing in a cost-effective manner. The value of DanTest QHRV analyses and health testing cannot be overstated as preventative tools and supplementary guides to overall patient health.

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Heart Rate Variability Analysis (HRV)
Heart rate variability (HRV) is a measure of variations in the heart rate. It is usually calculated by analyzing the time series of beat-to-beat intervals from ECG or arterial pressure tracings.

Various measures of heart rate variability have been proposed, which can roughly be subdivided into time domain, frequency domain and non-linear measures. HRV is regarded as an indicator of the activity of autonomic regulation of circulatory function. It also regarded as the definitive method of analyzing the activity of the autonomic nervous system. Alteration (mostly reduction) of HRV has been reported to be associated with various pathologic conditions like hypertension, hemorrhagic shock, and septic shock. It has found its role as a predictor of mortality after an acute myocardial infarction.

Time Domain
A simple example of a time domain measure is the calculation of the standard deviation of beat-to-beat intervals. Other time domain measures include root mean square of the differences between heart beats (rMSSD), NN50 or the number of normal to normal complexes that fall within 50 milliseconds, and pNN50 or the percentage of total number beats that fall with 50 milliseconds. SDNN has been strongly corelated to overall variability, while rMSSD relates to the parasympathetic nervous system activity on heart rate.

Frequency Domain
A common frequency domain method is the application of the discrete Fourier transform also known as the Fast Fourier transform, to the beat-to-beat interval time series. That expresses the amount of variation for different frequencies. Several frequency bands of interest have been defined in humans.

 

 

Details

 

  • Quantitative Sudomotor Axon Reflex Test (QSART)
    Quantitative Sudomotor Axon Reflex Test (QSART) is a test to evaluate the integrity of the postganglionic sudomotor system along the axon reflex to define the distribution of sweat loss. This is accomplished by the release of acetycholine into the skin which activates receptors on the eccrine sweat gland. The sweat response is recorded from four sites (forearm and 3 lower extremity sites) and assessed for deficits.

    The QSART is a test that measures the autonomic nerves that control sweating. The test is useful in assessing autonomic nervous system disorders, peripheral neuropathies and some types of pain disorders. The test requires a mild electrical stimulation on the skin called iontophoresis, which allows acetylcholine, a naturally occurring chemical, to stimulate sweat glands. The QSART measures the volume of sweat produced by this stimulation.

    QSART is used to diagnose:

    - Painful, small fiber neuropathy when nerve conduction test results are normal
    - Disturbances of the autonomic nervous system, which controls the sweat glands, heart, digestive system, other organs, and blood pressure
    - Complex pain disorders
    - Diabetic neuropathies
    - Enzyme disorders
    - RSD (Reflex Sympathetic Dystrophy, Complex Regional Pain Syndrome)
    - Dysautonomia
    - Pharmaceutical agents
    - Cosmetics/Consumer goods testing
    - Dermatological studies
    - Multiple System Atrophy (Shy-Drager syndrome)

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  • Sympathetic Skin Response (SSR)
    Sympathetic Skin Response (SSR) measures change of the electrical potential of the skin. The recorded skin potential comes from the activated eccrine sweat gland. The amplitude and configuration are adjusted by sweat gland epithelium and the overlying epidermis.

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  • Sudomotor sympathetic response
    BioScan SudoCheck provides information that determines the cardiometabolic risk in patients. The test, equivalent to a galvanic skin response stress test, measures the sweat glands' capacity to release chloride ions in response to an electrochemical activation.
    The advantages: BioScan SudoCheck does not require any patient preparation, such as blood drawing or fasting; it is non-invasive and delivers immediate results, with findings that are ready to use after a short and uncomplicated test of merely 2 minutes.
    BioScan SudoCheck has been developed for use by general practitioners, pharmacists, cardiologists and neurologists to assist in the effective screening of cardiometabolic risk in patients.

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  • Bioelectric Impedance Analysis (BIA)
    As a physician, you know that the Body Mass Index (BMI) by itself is not sufficient to analyze a patient's health status and body composition thoroughly.
    Fat, muscle, water and other important indicators of underlying medical conditions are not considered in the BMI.
    Reason enough for Medeia to develop exactly that - a new device that measures patients' body compositions - the "BCA" (Body Composition Analyzer). As a component of the BioScan SudoCheck, it produces all these measurements and values at medical science highest standard levels.

    As a result, now a tool exists that, in less than 20 seconds, can determine fat mass, extracellular and intracellular water, and skeletal muscle mass, all fundamental assessment components to aid an accurate patient evaluation. Simple, user friendly, and with medical precision, this device can conveniently be integrated into your examination routine.

    In order to make BioScan SudoCheck the optimal medical Body Composition Analyzer for working conditions in hospitals and medical practices, we looked beyond the many technical requirements and at the advantages and benefits that are valuable and of importance to medical staff and patients. We understood it had to be fast and easy to use and the measurement results had to be reproducible under normal clinical working conditions. That's' how we designed and build BioScan SudoCheck.

    The BioScan SudoCheck provides physicians and other users with a myriad of diagnostic options. Analytical modules provide accurate ratios for, for example extracellular to intracellular water, or fat mass to weight, and present doctors with indications of medical disorders that would otherwise need additional examinations to be diagnosed. The graphic presentation of the results is another benefit. It provides a summary and overview and helps visualize the data.

    Bioelectric Impedance Analysis (BIA) is not yet available in USA

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  • Electro Interstitial Scan
    It is recommended to test the functions of the device before measurement, to ensure that the connection to the patient is satisfactory and hardware and software are operating properly. With the onset of measurement, a weak DC current (200 uA) is used and an imposed voltage of 1V between the six tactile electrodes that performs a sequence of successive measurements on eleven pathways of the body. Starting from anode to cathode and then from cathode to anode, the software changes the polarity for each pathway and measures the conductance of each pathway. Six electrodes are placed symmetrically on the hands, feet and forehead of the patient and a direct current of 1V is applied. For a recording of 11 segments in measurement sequence, each electrode is first in cathode and then in anode (bipolar mode), transmitting the intensity in numeric format to a program that stores the information.
    A weak DC current, with the help of 6 tactile electrodes, is sending alternatively between 2 electrodes with a sequence, and a record of the electrical conductance of 11 pathways in the subject's body is displayed by the BioScan SudoCheck system.
    The BioScan SudoCheck system is a galvanic Skin response device that provides skin conductance measurements on the PC screen in accordance with the 21 CFR 882.1540.

    The device uses two techniques: The Bio Impedance Analysis (BIA) and the Bio Impedance Spectrometry (BIS).
    The purpose of BIA is the estimation of body composition and water balance but it is also used in cardiology and imaging.
    The BIS is another technique for the estimation the body composition and water balance, but it can also be used to estimate neurotransmitters.

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